Important safety notes

WARNING
Make sure absolutely no objects are obstructing the pedals' range of movement.
Keep the driver's footwell clear of all obstacles. If there are any floormats or carpets in the footwell, make sure the pedals still have sufficient clearance.
During sudden driving or braking maneuvers the objects could get caught between the pedals. You could then no longer brake or accelerate. This could lead to accidents and injury.

WARNING
On slippery road surfaces, never downshift in order to obtain braking action. This could result in drive wheel slip and reduced vehicle control. Your vehicle's ABS will not prevent this type of loss of control.

WARNING
It is dangerous to shift the automatic transmission out of parking position P or neutral position N if the engine speed is higher than idle speed. If your foot is not firmly on the brake pedal, the vehicle could accelerate quickly forward or in reverse. You could lose control of the vehicle and hit someone or something. Only shift into gear when the engine is idling normally and when your right foot is firmly on the brake pedal.

WARNING
HYBRID vehicles: It is imperative that you read the HYBRID Supplemental Operating Instructions included in your vehicle literature portfolio. You may otherwise not receive all necessary safety information and warning for the operation of your vehicle.

the engine's full performance until it has Warm up the engine quickly. Do not use the engine's full performance until it has reached operating temperature.
Only shift the automatic transmission to the desired drive position when the vehicle is stationary.
Where possible, avoid spinning the drive wheels when pulling away on slippery roads. You could otherwise damage the drive train.

below 68 °F (+20 °C), the maximum engine S 63 AMG: at low engine oil temperatures below 68 °F (+20 °C), the maximum engine speed is restricted in order to protect the engine. To protect the engine and maintain smooth engine operation, avoid driving at full throttle when the engine is cold.

    See also:

    BAS PLUS (Brake Assist System Plus)
    BAS PLUS is only available in vehicles equipped with DISTRONIC PLUS. Observe the "Important safety notes" section. At speeds above approximately 20 mph (30 km/h), BAS PLUS assists ...

    Upshifting
    In manual drive program M, the automatic transmission does not shift up automatically even when the engine limiting speed for the current gear is reached. When the engine limiting speed is ...

    ESP® trailer stabilization
    If your vehicle with trailer (vehicle/trailer combination) begins to lurch, you can only stabilize the vehicle/trailer combination by depressing the brake firmly. In this situation, ESP® assists ...