Safety, Reliability & Mileage

Because the E-Class has been redesigned, we don't yet have predicted reliability ratings for this model. Furthermore, the 2010 E-Class hasn't yet been crash-tested by our preferred source, the Insurance Institute for Highway Safety. All-wheel-drive models are estimated to get 17/24 mpg city/highway — slightly less than models without all-wheel drive.

Standard safety features for the E350 4Matic include antilock brakes, an electronic stability system, side-impact airbags, and side curtain airbags that cover both rows of seats. As mentioned, our test model also came with a few optional safety features, including Blind-Spot Assist, Lane-Keeping Assist, Attention Assist, and an adaptive cruise control system called Distronic Plus with Pre-Safe Brake, which can apply the brakes to slow the car all the way to a stop if needed. Click here to see a full list of safety features.

About the Distronic/Pre-Safe system: It works. In one of my highway drives, someone decided to exit the highway by cutting across three lanes of traffic in front of me and several other cars. I saw what was happening in time to have my foot on the brake pedal, and I'd like to say I was so quick I was able to properly apply the brakes — but the system was quicker. Let's hope I never get to test the airbags.

    See also:

    Please bear the following in mind
    For safety reasons, Mercedes-Benz recommends that you only use Tires and wheels which have been approved by Mercedes-Benz specifically for your vehicle. These tires have been specially adapted f ...

    Important safety notes
    WARNING Do not adjust the steering wheel while driving. Adjusting the steering wheel while driving could cause the driver to lose control of the vehicle. The electrical steering wheel adj ...

    Automatic anti-glare mirrors
    WARNING If incident light from headlamps is prevented from striking the sensor in the rear-view mirror, for instance, by luggage piled too high in the vehicle, the mirror's automatic ant ...