All G 500 model versions feature the COMAND APS infotainment system with a built-in six-disc DVD changer. The system's specification includes hard-disc navigation with a tracking function outside digitised areas, telephone operation, plus a special off-road menu. COMAND APS also incorporates the new LINGUATRONIC system with extended functionality. The voice-operated control now recognises whole-word commands, which can be spoken by anyone without the need to train the system first. The system is simply activated by means of a control on the right of the multifunction steering wheel. It can be used for making a call by saying the telephone number, controlling the audio system, calling up the global address book and operating the navigation system. COMAND APS may also be combined with the optional TV tuner and reversing camera.

There are other equipment options too: for the ultimate in listening pleasure there is the Harman Kardon® Logic7® surround sound system with 12 high-performance speakers and an output of 450 watts, while climatised seats offer enhanced seating comfort for the driver and front passenger.