Important safety notes

Severe conditions (e.g. strong air pollution) WARNING
Severe conditions (e.g. strong air pollution) may require replacement of the filter before its scheduled replacement interval. A clogged filter will reduce the air volume to the interior and the windows could fog up, impairing visibility and endangering you and others.
Have a blocked filter replaced at a Mercedes- Benz Center as soon as possible.

Follow the recommended settings for heating WARNING
Follow the recommended settings for heating and cooling given on the following pages.
Otherwise, the windows could fog up, impairing visibility and endangering you and others.

Automatic climate control controls the temperature and the humidity of the vehicle interior and filters out undesirable substances from the air.

Automatic climate control is only operational when the engine is running. Optimum operation is only achieved if you drive with the side windows and sliding sunroof/panorama roof with power tilt/sliding panel closed.

Ventilate the vehicle for a brief period Ventilate the vehicle for a brief period during warm weather, e.g. using the convenience opening feature.
This will speed up the cooling process and the desired vehicle interior temperature will be reached more quickly.

The integrated filter can filter out most The integrated filter can filter out most particles of dust and completely filters out pollen. A clogged filter reduces the amount of air supplied to the vehicle interior. For this reason, you should always observe the interval for replacing the filter, which is specified in the Service Booklet. As it depends on environmental conditions, e.g. heavy air pollution, the interval may be shorter than stated in the Service Booklet.

    See also:

    Resetting to factory settings
    For safety reasons, the Daytime Running Lights: function in the Lights submenu is only reset when the vehicle is stationary. – Press the or button on the steering wheel to select the Setting ...

    AMG adaptive sport suspension system
    General notes AMG adaptive sport suspension system is available for the E 63 AMG model. ...

    Activating RACE START
    •► Depress the brake pedal with your left foot, and keep it depressed. •► Turn the drive program selector clockwise until the RS lamp lights up. The multifunction display shows the RAC ...