Switching to navigation mode
Press the 
function button once
or
twice.
or
Select Navi in the main function bar by
sliding 
and turning
the COMAND
controller and press 
to confirm.
In both cases, you will see the map either
with or without the menu shown.
Map showing the menu; route guidance inactive
1 Current vehicle position
Map without the menu; route guidance inactive
1 Current vehicle position
2 Map orientation selected
3 Map scale selected
"Route guidance active" means that you have entered a destination and that COMAND has calculated the route. The display then shows the route, changes of direction and lane recommendations. Navigation announcements guide you to your destination.
"Route guidance inactive" means that no destination has been entered and that no route has been calculated.
See also:
Setting a speed
WARNING
Keep in mind that it may take a brief moment
until the vehicle has made the necessary
adjustments.
Increase or decrease the set vehicle speed to
a value that the prevailing road cond ...
Interior
As much as I like how the CL looks from the outside, it's on the inside that
Mercedes outdoes the competition: Everything you see or touch looks and feels
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Deactivating
Press and hold the closing button () in the tailgate until you
hear two short tones.
...