In the interior, too, Mercedes-Benz developers and designers perfected the Mercedes-Benz CL-Class, paying careful attention to detail. A total of four different kinds of fine wood open up the possibilities for perfectly matched material and color concepts: a choice of light or dark high-gloss burl walnut, black ash and high-gloss brown poplar on the CL600. Important to note: in accordance with Mercedes-Benz' corporate philosophy of sustainability, the Mercedes-Benz CL-Class uses only European wood from renewable forestry sources. Most of the wood components are hand-made and matched individually for color and grain by experienced craftsmen.

The seating materials found in the new CL-Class are of the most exquisite quality. There is a choice of four tasteful color combinations for the vehicle interior: black premium leather, savanna/cashmere premium leather, ash/grey premium leather, sahara beige/black premium leather.

The multifunction wood/leather steering wheel of the Mercedes-Benz CL-Class has also been modified by the Mercedes-Benz designers: the rim and airbag module are lined with soft nappa leather as standard. The new, flatter airbag module also lends a sporty touch to the multifunction wood/leather steering wheel sewn with sophisticated double stitching.

Apart from this, Mercedes-Benz makes more use of light as a styling element in the vehicle interior. Standard ambient lighting provides a choice between three lighting moods: solar (amber), neutral (white) and polar (ice blue).